Erlotinib-associated dermatological toxicity
نویسندگان
چکیده
منابع مشابه
Acute Fatal Liver Toxicity under Erlotinib
We describe the case of a never-smoker who received second-line erlotinib as a treatment for his non-small cell lung cancer. Within one month, acute hepatic failure developed as well as a thrombotic-thrombocytopenic microangiopathy, with fatal outcome. In patients with non-small cell lung cancer, hepatic toxicity of erlotinib is a rare but severe complication; so far three fatal cases have been...
متن کاملDermatological toxicity in women with breast cancer undergoing chemotherapy treatment.
This study aimed to analyze the occurrence of skin toxicity caused by drugs used in the protocol of neoadjuvant and adjuvant chemotherapy among women with breast cancer. Patient records of 72 women who were subject to this therapy between 2003 and 2006 were assessed. Of the 558 cycles of chemotherapy, 152 adverse events were registered. There were 37 registrations of dermatological toxicity, of...
متن کاملErlotinib Induced Fatal Interstitial Lung Disease: An Underreported Toxicity
Lung cancer is the leading cause of cancer-related mortality around the world, with 85% of cases identified as non-small-cell lung cancer (NSCLC). Adenocarcinoma is the most common histologic subtype in the US and accounts for more than 50% of all NSCLC. Activating mutations in the epidermal growth factor receptor (EGFR) tyrosine kinase are found in approximately 15% of NSCLC adenocarcinoma in ...
متن کاملMeta-analysis of dermatological toxicities associated with sorafenib.
A meta-analysis was performed to determine the type, incidence and risks of dermatological toxicities associated with the multikinase inhibitor sorafenib. A literature search was performed using the electronic databases PubMed and EMBASE, and conference abstracts published by the American Society of Clinical Oncology. Eligible studies included prospective phase II or III clinical trials, and ex...
متن کاملDental Sealant Toxicity: Neurocutaneous Syndrome (NCS), a dermatological and neurological disorder
Neurocutaneous syndrome (NCS), a newly discovered toxicity disorder, is described in light of our new understanding of its relationships with the causative agents included in the dental liners used in afflicted patients. NCS is characterized by neurological sensations, pain, depleted energy and memory loss as well as itchy cutaneous lesions that may invite various opportunistic infections. Comp...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: QJM
سال: 2012
ISSN: 1460-2725,1460-2393
DOI: 10.1093/qjmed/hcs164